Vasopressin and pair-bond formation: genes to brain to behavior.
نویسندگان
چکیده
Microtine rodents provide an excellent model for the study of the neurobiology of social bonds. In this review, we discuss how the presence of a microsatellite sequence in the prairie vole vasopressin receptor gene may determine vasopressin receptor binding patterns in the brain and how these patterns may in turn affect social behavior.
منابع مشابه
Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster).
Male prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this behavior is regulated by the neuropeptide vasopressin (AVP). The authors report that AVP in the lateral septum is important for pair bond formation. Administration of an AVP V1a receptor antagonist in the lateral septum blocked mating-induced pair bonding, whereas administration of AVP induce...
متن کاملNeurochemical regulation of pair bonding in male prairie voles.
Pair bonding represents social attachment between mates and is common among monogamous animals. The prairie vole (Microtus ochrogaster) is a monogamous rodent in which mating facilitates pair bond formation. In this review, we first discuss how prairie voles have been used as an excellent model for neurobiological studies of pair bonding. We then primarily focus on male prairie voles to summari...
متن کاملFacilitation of affiliation and pair-bond formation by vasopressin receptor gene transfer into the ventral forebrain of a monogamous vole.
Behaviors associated with monogamy, including pair-bond formation, are facilitated by the neuropeptide vasopressin and are prevented by a vasopressin receptor [V1a receptor (V1aR)] antagonist in the male prairie vole. The neuroanatomical distribution of V1aR dramatically differs between monogamous and nonmonogamous species. V1aR binding is denser in the ventral pallidal region of several unrela...
متن کاملAre plasma oxytocin in women and plasma vasopressin in men biomarkers of distressed pair-bond relationships?
Young adults in couple (pair-bond) relationships reported on the positive and negative aspects of their relationships and had blood drawn and assayed for oxytocin and vasopressin. Elevated plasma oxytocin was associated with distress in the pair-bond relationship for women, but not for men. Vasopressin, which is closely related to oxytocin in molecular structure and significantly related to mal...
متن کاملSpecies-specific patterns of nonapeptide brain gene expression relative to pair-bonding behavior in grouping and non-grouping cichlids.
Comparative studies have revealed that vasopressin-oxytocin pathways are associated with both pair bonding and grouping behavior. However, the relationship between pair bonding and grouping behavior remains unclear. In this study, our aim was to identify whether two species that differ in grouping behavior display a corresponding difference in their pair bonds, and in the underlying vasopressin...
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ورودعنوان ژورنال:
- Physiology
دوره 21 شماره
صفحات -
تاریخ انتشار 2006